WHY ARE WE MAGNESIUM DEFICIENT?
                
The Weekend Warrior, Over training
It has been found that exercisers that feel weak and tired are highly
 likely to be suffering from mineral deficiency. Magnesium is lost via 
sweat and can bring on fatigue, muscle cramps, impaired glucose and 
oxygen transport into muscle cells, especially the heart. Sweating from 
exercise or saunas, steam rooms, when done regularly require the regular
 replacement of magnesium. In severe cases, with extreme athletes, body 
builders and long distance runners, depletion of heart tissue magnesium 
can cause Sudden Cardiac Death (SCD), myocardial infarction, angina 
pectoris, and heart arrhythmias.
The mechanism of sudden death after a stressful event can be traced 
to magnesium depletion that causes oxygen depletion in the heart muscle,
 and increased arrhythmia from increased catecholamine output.  
Magnesium loss was the first electrolyte derangement seen even before 
potassium loss. Intravenous magnesium therapy has increased survival 
rates.
Without optimum “cellular magnesium” levels (our ATP/cellular energy 
synthesis) optimum muscle contraction and oxygen utilization suffers, 
sometimes with fatal consequences. Therefore, over-training, 
overexertion, excessive sweating, either done in one event or done 
repetitively, especially without sufficient electrolyte replacement will
 burn magnesium at a faster rate and send us into intracellular 
deficiency of magnesium.
A runner need not drop dead on the course of sudden cardiac death to 
be magnesium deficient. Sudden cardiac death strikes the youth and prime
 even post event when intracellular heart magnesium is not replenished. 
Over training, and not becoming aware of the state of one’s intracellular
 magnesium could be fatal as you might not have other magnesium 
deficient symptoms such as cramping of muscles to warn you of a problem!
In a treadmill study of 44 healthy male athletes and 20 untrained 
men, the athletes’ their average maximum oxygen consumption was higher, 
their work capacity increased 50% and they had lower lactate after 
exercise than the untrained men. This is to be expected. What was not 
expected was to find a correlation between oxygen consumption and serum 
magnesium. When magnesium was depleted, oxygen consumption declined 
along with endurance and performance. Therefore, magnesium’s role in 
facilitating oxygen delivery to muscles is significant.
Another interesting study was performed on marathon runners measuring
 their free fatty acid levels during a 26 mile race and their serum 
magnesium levels. They compared their values against an untrained runner
 who was given magnesium supplementation of 375mg/day for a week before 
the run. The marathon runners showed increasing levels of free fatty 
acids as they approached 26 miles (indicating increasing levels of 
stress perceived by the body and stress hormones released as a result) 
and corresponding decreasing levels of serum magnesium levels, but not 
with the untrained runner! Because he was talking magnesium, his body 
was able to burn the magnesium to ward of an increase in stress 
hormones. He had lower stress hormone excretion, less lactic acid build 
up and more magnesium to spare. The end result, he ended the race 
healthier metabolically than the marathon runners who did not take 
magnesium supplementation! (Pratt K, Moody ML, Cinlee RK, Rueddel H, 
Frnz KB; Changes in serum free fatty acids and magnesium during a 
marathon. Magnesium 4:207-208, 1985.
Another study found that the stress of marathon running had caused 
these runners to have increased platelet aggregation factor TXB2 levels 
as serum magnesium levels were depleted. TXB2 causes vasoconstriction as
 well as sticky blood. Clearly, magnesium replacement during runs are as
 or even more important than plain water to prevent dehydration during 
and after a race!
Additional silent damage, the consequence of magnesium deficiency, 
induced by strenuous exercise, leads to calcium overload, resulting in 
cell membrane lipid anti-per oxidative activity. In lay terms, this 
means magnesium deficiency increases one’s free radical activity, 
leading to increased stress on one’s heart muscle, leading to 
aggravation of all heart conditions. Free radical accumulation from 
extreme exercise and magnesium deficiency was buffered by taking vitamin
 E and magnesium. The fact that extreme athletes and those regularly 
engaging in strenuous exercise do not have a longer lifespan may be 
attributed to magnesium depletion leading to increased oxidative stress 
and metabolic induced inflammation which could be avoided by paying 
attention to one’s magnesium!
Therefore, even before we begin to push our bodies for strenuous 
exercise, if our tissue magnesium stores are low, we will notice more 
fatigue, decreased exercise capacity despite regular exercise. We will 
feel dragy, winded and have a hard time picking our energy up from 
exercise. If we continue to push our bodies, we will then suffer muscle 
stiffness, spasms or strains and sprains from the stiffness that results
 from low intracellular magnesium. Biochemically, we will increase our 
stress hormones even more when we are magnesium deficient, and suffer 
more free radical synthesis, increased cholesterol! and oxygen depletion
 to our heart muscle. However, our heart tissue can become deficient in 
magnesium before other tissues of the body. Thus we might not have any 
body symptoms to warn us of a more serious heart muscle deficiency. The 
consequences to the heart can be fatal. Beware the stressed executive 
that dies on his/her treadmill as this can be the silent vicious cycle of mineral depletion.
Stress
We all underestimate stress because we live in it daily and take it 
as part of our daily lives. But stress takes it’s toll on us. Stress, 
both physical and mental aggravation, frustration, irritability, causes 
you to burn magnesium at a faster rate. Stress makes your body more 
acidic. Magnesium is used to buffer that acid. Therefore, stress causes 
you to burn magnesium faster to neutralize the acid.
Our adrenals and nerves secrete stress hormones called catecholamines
 and corticosteroids, when under emotional or physical stress. Do you 
know when your body is releasing these stress hormones? No! Like using 
up the gasoline in one’s car, it’s a slow and steady drain. These stress
 hormones cause the loss of cellular magnesium leading directly to 
problems with cellular energy production, and skeletal and heart muscle 
performance that lead to blood clotting and heart arrhythmias.
There was a study comparing Type A and Type B individuals that found 
that Type A personalities excreted more stress hormones in response to 
noise and mental stress and depleted their magnesium faster than Type 
Bs! This explains the increased risk among Type A’s for mitral valve 
prolapse, hypertension, and cardiovascular disease. Becoming aware of 
our stressors, managing how we react to stress and increasing one’s 
magnesium will help to buffer us from daily stress.
The bad thing about stress is that as it depletes you silently of your
 magnesium, low intracellular magnesium causes the excretion of MORE 
stress hormones. Therefore, magnesium is protective in preventing 
excessive release of these stress hormones! In addition, adrenal stress 
that causes the adrenals to release the hormone epinephrine (our fight 
or flight hormone) burns intra cellular magnesium at such a fast rate 
that one quickly becomes depleted.
What causes our adrenals to release more epinephrine? Physical 
stress, as in strenuous exercise, strenuous training, runners, 
especially marathon runners and those suffering from prolonged 
emotional, familial, and work stress. Please see our other articles 
about cortisol function.
The stress hormones also signal the body to release free fatty acids 
as an energy source. However, there is a price to pay for this extra 
needed energy boost during times of stress. These free fatty acids bind 
and inactivate magnesium in your blood stream and heart, slowing down 
the transport of glucose and oxygen into muscles and prevent magnesium 
from being used by the Kreb’s cycle to make ATP as energy, using a more 
inefficient free fatty acid source for energy. Fatigue, cellular oxygen 
deprivation especially of heart tissue, increased free radicals, loss of
 glucose transport, and our cholesterol ratios are thrown out of 
balance. We hit a wall energetically.
Imagine the typical stressed executive, by nature of his/her 
lifestyle is already burning magnesium at a faster rate because of their
 adrenal output of stress hormones. He wakes up and has a high acid 
breakfast of coffee, eggs and a muffin that consumed intracellular 
magnesium to neutralize the breakfast. He dashes to work out already 
feeling short on time. Then this driven executive goes to the gym and 
does a rigorous 30 minute treadmill run, sweating out magnesium and 
continuing to push his adrenals to excrete epinephrine for energy to 
keep up with his strenuous activity. If the night before, he had to 
entertain clients and had several alcoholic drinks (causing him to 
urinate extra magnesium) and he ate a large steak for dinner (high acid 
meal), then his lifestyle continues to deplete him of magnesium. If 
there was a work deadline pending the next few days, or this executive 
had a fight with his wife the night before or with his kids that morning
 before hitting the gym, his body is in peak demand for magnesium. 
Depending on the duration of his life stressors and duration of his acid
 diet, combined with his life stressors, it becomes no surprise when 
this executive drops dead on his treadmill from sudden cardiac arrest, 
in large part from severe depletion of myocardial intracellular 
magnesium.
If this stressed executive does not drop dead that morning, then 
continued stress hormones coupled with consumed intracellular magnesium 
cause calcium overload in the tissues. This will lead to heart 
arrhythmias and calcium deposits in blood vessels, accelerating 
atherosclerosis, the development of kidney stones and bone spurs, 
accelerating osteoporosis for men and women. It will push his 
cholesterol out of optimal range despite his efforts to eat a heart 
healthy diet!
Now that we know that our food and lifestyle predisposes us to 
magnesium wasting, what do we have to fear aside from sudden cardiac 
death with chronic depletion of magnesium?
Part 3 will discuss why magnesium is so essential to our health. It 
will also go into what medical conditions pre-dispose you to magnesium 
deficiency and discuss specific conditions and their mechanism of 
depleting us of magnesium, in turn making the condition worse!
Please note:
Information on this site is provided for informational purposes only and
 is not intended as a substitute for the advice provided by your 
physician or other healthcare professional. You should not use the 
information on this site for diagnosing or treating a health problem or 
disease, or prescribing any medication or other treatment.
Source:
http://chronicfatigueandnutrition.com/vitamins-and-minerals/why-are-we-magnesium-deficient/ 
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