A recent study conducted by the Department of Human Nutrition at Virginia Polytechnic Institute and State University, examined the effects of supplemental docosahexaenoic acid (DHA) on inflammation, soreness and other markers of muscle damage following eccentric exercise. Forty-one untrained men consumed either 2 g of DHA or a placebo each day, for a total of 28 days, prior to engaging in a bout of aggressive eccentric work focusing on the elbow flexors (biceps).
The biceps were used because delayed-onset muscle soreness (DOMS) and muscle damage tends to be greatest when performing eccentric work with smaller muscle groups. The researchers examined the impact of DHA on isometric strength, range of motion (ROM), DOMS and various blood markers associated with inflammation and muscle damage. Isometric strength, ROM and DOMS were assessed on the day of the exercise bout as well as 2, 3, 4, 7, 12, and 17 days later. Blood markers were also measured on the day of the exercise bout as well as 2, 4, 7, 12 and 17 days later.
In the first three days after the eccentric exercise bout DHA supplementation reduce the serum creatine kinase and interleukin-6 responses (12.5% and 32%, respectively), but it did not positively impact isometric strength, ROM or DOMS. When examining all of the total data compiled over a 17-day period following the eccentric exercise bout, DHA use seemed to slightly minimize the impact of DOMS as well as serum creatine kinase levels when compared to the placebo.
Source:
http://www.ncsf.org/newsarticles/0-366/docosahexaenoic-acid-supplementation-and-muscle-damage.aspx
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